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Nature Safe Effective Health Tasty Efficient
8 Years
| Ask Lasest Price | |
| Brand Name : | complex |
| Model Number : | BGH-337 |
| Certification : | ISO9001/Halal/Kosher |
| Price : | US$61/kg |
| Payment Terms : | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability : | 5000000kg per year |
| Delivery Time : | 3 workdays after payment |
China Manufacturer Anti Cancer Medicine Tretinoin Powder
Product Details
Successfully treating acute promyelocytic leukemia (APL) with Tretinoin was a major breakthrough in APL therapy. It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor (RAR) gene to the promyelocytic leukemia (PML) gene.This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia. ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.
Product Analysis
| Item | Specification | Result | Method |
| BasicProduct Information | |||
| Product name | tretinoin powder | ||
| Part of the Plant | body | Conform | / |
| Country of Origin | China | Conform | / |
| Organoleptic Data | |||
| Appearance | Fine powder | Conform | NLS-QCS-1008 |
| Color | white powder with slight yellow cast | Conform | GB/T 5492-2008 |
| Odor& Taste | Characteristic | Conform | GB/T 5492-2008 |
| Process Data | |||
| Solvent(s) Used | Water and ethyl alcohol | Conform | / |
| Extract ration | / | Conform | |
| Content | Paeoniflorin≥98% | 98.12 | |
| Drying Method | Spray drying | Conform | / |
| Excipient | Maltodextrin | Conform | / |
| Physical Characteristics | |||
| Particle Size (80 mesh) | 98.0%pass 80mesh | Conform | GB/T 5507-2008 |
| Moisture | <5.0% | 2.8% | GB/T 14769-1993 |
| Ash Content | <4.0% | 1.4% | AOAC 942.05, 18th |
| Solvent Residue | Eur. Pharm | Conform | NLS-QCS-1007 |
| Heavy Metals | |||
| Total Heavy Metals | <10 ppm | Conform | USP <231>, method II |
| Arsenic | <1.0 ppm | Conform | AOAC 986.15, 18th |
| Lead | <1.0 ppm | Conform | AOAC 986.15, 18th |
| Mercury | <0.5 ppm | Conform | AOAC 971.21, 18th |
| Pesticide Residue | |||
| 666 | <0.2ppm | Conform | GB/T5009.19-1996 |
| DDT | <0.2ppm | Conform | GB/T5009.19-1996 |
| Microbiology | |||
| Total Plate Count | <1,000cfu/g | 17cfu/g | AOAC 990.12, 18th |
| Total Yeast & Mold | <100cfu/g | 8cfu/g | FDA (BAM) Chapter 18, 8th Ed. |
| E. Coli | Negative | Negative | AOAC 997.11, 18th |
| Salmonella | Negative | Negative | FDA (BAM) Chapter 5, 8th Ed. |
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